Investigating Neural Differentiation of Mouse P19 Embryonic Stem Cells in a Time-Dependent Manner by Bioinformatic, Microscopic, and Transcriptional Analyses

By applying the in vitro differentiation of mouse pluripotent P19 cell line into neuron-like cells through retinoic acid treatment, the roles of some genes including DNMT3B, ICAM1, IRX3, JAK2, LHX1, SOX9, TBX3 , and THY1 in neural differentiation was investigated.