A Bioengineered Probiotic for the Oral Delivery of a Peptide Kv1.3 Channel Blocker to Treat Rheumatoid Arthritis

By
Laurisa Dohm
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0
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The authors developed a genetically engineered probiotic delivery system that delivered a peptide to the intestinal tract with high efficacy. They constructed an inducible system in the probiotic Lactobacillus reuteri to secrete the Kv1.3 potassium blocker ShK-235.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
Abstract