Osteocalcin Inhibits Myocyte Aging through Promotion of Starvation-Induced Autophagy via IL-6/STAT3 Signaling

Investigators revealed that compared to control and serum-starved cells, osteocalcin treatment significantly increased the relative expression of LC3-II/LC3-I protein, the numbers of autophagosomes, and levels of intracellular reactive oxygen species.