NewslettersESC & iPSC NewsRUNX1 Upregulation Causes Mitochondrial Dysfunction via Regulating the PI3K-Akt Pathway in iPSC from Patients with Down SyndromeBy Noshin Noorjahan - January 11, 20230179Scientists investigated whether runt-related transcription factor 1 (RUNX1) played a critical role in mitochondrial dysfunction in Down syndrome and explored the mechanism by which RUNX1 affected mitochondrial functions.[Molecules and Cells]Abstract