KCNH2 Encodes a Nuclear-Targeted Polypeptide That Mediates hERG1 Channel Gating and Expression

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Investigators identified a non-conducting KCNH2-encoded polypeptide, hERG1NP, that was upregulated in immature cardiomyocytes, and its targeting to the nucleus indirectly modulated hERG1 gating.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
Abstract