Evaluation of Poly (Lactic-Co-Glycolic Acid) Nanoparticles to Improve the Therapeutic Efficacy of Paclitaxel in Breast Cancer
PLGA-PTX nanoparticles were assayed in breast cancer cell lines, breast cancer stem cells, and multicellular tumor spheroids analyzing cell cycle, cell uptake, and α-tubulin expression.
[British Journal of Cancer] The immunoproteasome subunit LMP7 was silenced by using gene knockout or inhibited by the epoxyketone inhibitor ONX 0914 in a mouse castration-resistant prostate cancer (CRPC) tumor graft model and in interferon-γ-pretreated human CRPC cell lines in vitro.
[British Journal of Cancer] 582 mCRPC patients undergoing first-line abiraterone therapy from four institutions were sorted by three phases: discovery, training, and validation.
[International Journal of Radiation Oncology*Biology*Physics] Researchers performed an international multi-institutional retrospective study of 277 men with metachronous oligometastatic castration-sensitive prostate cancer who underwent targeted DNA sequencing of their primary/metastatic tumor.