Application of Nanomaterials in Stem Cell-Based Therapeutics for Cardiac Repair and Regeneration
Investigators discuss the current status and limitations of stem cells and cell-derived exosomes/micro RNAs based cardiac therapy, and evaluate the advantages and disadvantages of the relevant nanomaterials.
[Mucosal Immunology] Investigators review novel findings on the emerging role of mesenchymal cells in this process using insights gained from lineage tracing approaches, Cre-based genes deletion and single cells transcriptomics.
[Cell Death Discovery] Human hepatoma PLC/PRF/5-ASBT and THP1 cell lines or primary mouse hepatocytes were used for mechanistic studies. Hepatic TNFRSF12A expression was markedly increased in obstructive cholestasis or primary biliary cholangitis patients.