Transcriptional and Functional Effects of Lithium in Bipolar Disorder iPSC-Derived Cortical Spheroids

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Since brain cortex abnormalities are strongly associated with bipolar disorder (BD), scientists specifically generated induced pluripotent stem cell-derived human cortical spheroids from healthy controls and BD patients and studied the effects of lithium treatments at the transcriptional and functional level.
[Molecular Psychiatry]
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