VGLL4 and MENIN Function as TEAD1 Corepressors to Block Pancreatic β Cell Proliferation

Researchers demonstrated that while β cell-specific TEAD1 deletion resulted in a cell-autonomous increase of β cell proliferation, β cell-specific deletion of its canonical coactivators, YAP and TAZ, did not affect proliferation, suggesting the involvement of other cofactors.
[Cell Reports]
Full ArticleGraphical Abstract
spot_img

Stay up-to-date with your field!

Subscribe for free weekly science newsletters.

Related News