EGFR and Lyn Inhibition Augments Regorafenib Induced Cell Death in Sorafenib Resistant 3D Tumor Spheroid Model

Investigators utilized sorafenib resistant Huh7 cell line and LX2 hepatic stellate cell line to establish a sorafenib resistant 3D tumor spheroid model which could be used to test second-line treatment options.
[Cellular Signalling]
AbstractGraphical Abstract

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