MSCs-Derived Apoptotic Extracellular Vesicles Promote Muscle Regeneration by Inducing Pannexin 1 Channel-Dependent Creatine Release by Myoblasts

Scientists extracted apoptotic extracellular vesicles derived from mesenchymal stem cells (MSCs-ApoEVs) to treat cardiotoxin-induced tibialis anterior injury and found that MSCs-ApoEVs promoted muscles regeneration and increased the proportion of multinucleated cells.