The Immunomodulatory Molecule TIGIT Is Expressed by Chronic Lymphocytic Leukemia Cells and Contributes to Anergy

Scientists studied the expression of T-cell immunoreceptor with Ig and ITIM domains (TIGIT) and CD226 in a cohort of 115 chronic lymphocytic leukemia patients and reported the expression of TIGIT and CD226 by leukemic cells.