An Antisense Oligonucleotide-Loaded Blood–Brain Barrier Penetrable Nanoparticle Mediating Recruitment of Endogenous Neural Stem Cells for the Treatment of Parkinson’s Disease

ZAAM, an antisense oligonucleotide-loaded, aptamer Apt 19S-conjugated, neural stem cell membrane-coated nanoparticle, was developed for the targeted treatment of Parkinson’s disease.