Down-Regulation of KLF2 in Lung Fibroblasts Is Linked with COVID-19 Immunofibrosis and Restored by Combined Inhibition of NETs, JAK-1/2 and IL-6 Signaling

Scientists investigated the effect of disease microenvironment on the fibrotic potential of human lung fibroblasts and its association with Kruppel-like factor 2 (KLF2) expression.