Single-Cell Landscape Highlights Heterogenous Microenvironment, Novel Immune Reaction Patterns, Potential Biomarkers and Unique Therapeutic Strategies of Cervical Squamous Carcinoma, Human Papillomavirus-Associated (HPVA) and Non-HPVA Adenocarcinoma

Using single-cell RNA and T-cell receptor sequencing, researchers investigated the transcriptomic atlas of several types of cancer that are typically treated identically to squamous cell carcinoma. The promalignant properties of the structural cells were studied using organoids.