NSUN2 Alleviates Doxorubicin-Induced Myocardial Injury through Nrf2-Mediated Antioxidant Stress

In vitro, H9C2 cells were transfected with NSUN2 siRNA or overexpressed lentivirus and then treated with 500 ng/ml doxorubicin. After 24 h, the changes in reactive oxygen species, apoptosis, and NSUN2 expression were detected.