Hedgehog and PDGF Signaling Intersect during Postnatal Lung Development

Scientists identified Hedgehog/platelet-derived growth factor (HH/PDGF) targets in several postnatal lung mesenchymal cell populations, including myofibroblasts, by single-cell transcriptomic analysis. Collectively, their data indicated that HH and PDGF signaling intersected to support myofibroblast/fibroblast function during secondary alveolar septum formation