Plant miRNA Osa-miR172d-5p Suppressed Lung Fibrosis by Targeting Tab1

Researchers identified osa-miR172d-5p, a plant-derived microRNA (miR), as a potent anti-fibrotic miR. In silico analysis followed by an in vitro assay based on human lung fibroblasts demonstrated that osa-miR172d-5p suppressed the gene expression of TGF-β activated kinase 1 binding protein 1 (Tab1).