NewslettersImmunology of Infectious Disease NewsHuman IRF1 Governs Macrophagic IFN-γ Immunity to MycobacteriaBy Laurisa Dohm - February 8, 20230219The authors studied unrelated children with inherited complete IRF1 deficiency and early-onset, multiple, life-threatening diseases caused by weakly virulent mycobacteria and related intramacrophagic pathogens.[Cell]Full Article