NewslettersESC & iPSC NewsPolycomb Protein RYBP Activates Transcription Factor Plagl1 during In Vitro Cardiac Differentiation of Mouse Embryonic Stem CellsBy lbeveridge - February 8, 20230276The authors reported that RING1 and YY1 binding protein (RYBP) was essential for mouse embryonic development and that Rybp null mutant ESCs cannot form contractile cardiomyocytes in vitro.[Open Biology]Full Article