A Whole-Genome Scan for Artemisinin Cytotoxicity Reveals a Novel Therapy for Human Brain Tumors

Using multiple model systems of human brain tumor development, such as cerebral glioblastoma organoids, and patient-derived tumor spheroids, scientists sensitized cancer cells to dihydroartemisinin using the clinically approved porphyrin enhancer and surgical fluorescence marker 5-aminolevulinic acid.