Release of Extracellular Superoxide Dismutase into Alveolar Fluid Protects against Acute Lung Injury and Inflammation in Staphylococcus aureus Pneumonia

Scientists hypothesized that arginine to glycine at position 213 substituted extracellular superoxide dismutase variant protected against lung injury and inflammation via blockade of neutrophil-recruitment in an infectious model of methicillin-resistant S. aureus pneumonia.