Crosstalk between Protein Kinase C α and Transforming Growth Factor β Signaling Mediated by Runx2 in Intestinal Epithelial Cells

Scientists identified a novel crosstalk between PKCα and TGFβ signaling. RNA-Seq analysis of non-transformed intestinal crypt-like cells and colorectal cancer cells identified TGFβ receptor 1 as a target of PKCα signaling.