Slc11a1 Gene Polymorphism Influences Dextran Sulfate Sodium (DSS)-Induced Colitis in a Murine Model of Acute Inflammation

Researchers investigated the possible modulating effect of the Slc11a1 R and S variants in DSS-induced colitis by using low acute inflammatory responses (AIRmin) mice homozygous for Slc11a1 R (AIRminRR) or S (AIRminSS) alleles.