T Cell-Independent Eradication of Experimental Glioma by Intravenous TLR7/8-Agonist-Loaded Nanoparticles

The authors investigated a β-cyclodextrin nanoparticle formulation, encapsulating the Toll-like receptor 7 and 8 agonist R848, to reprogram myeloid cells in the glioma microenvironment.