Activating Transcription Factor-2 Supports the Antioxidant Capacity and Ability of Human Mesenchymal Stem Cells to Prevent Asthmatic Airway Inflammation

Researchers activating transcription factor-2, a cAMP-response element binding protein, played a crucial role in maintaining the level and activity of Glutathione in human MSCs by crosstalking with nuclear factor erythroid-2 like-2, a well-known master regulator of cellular redox homeostasis.