The Alarmin Interleukin-33 Promotes the Expansion and Preserves the Stemness of Tcf-1⁺ CD8⁺ T Cells in Chronic Viral Infection

Studying CD8+ T cell differentiation in mice with chronic viral infection, the authors identified the alarmin interleukin-33 as pivotal for the expansion and stem-like functioning of stem-like CD8+ T cells, as well as for virus control.