Synergistic Effect of HDAC Inhibitor Chidamide with Cladribine on Cell Cycle Arrest and Apoptosis by Targeting HDAC2/c-Myc/RCC1 Axis in Acute Myeloid Leukemia

Cell counting kit-8 assays and Chou-Talalay’s combination index were used to examine the synergistic effect of Chidamide and Cladribine on AML cell lines and primary AML cells.