Novel Causative Variants of VEXAS in UBA1 Detected through Whole Genome Transcriptome Sequencing in a Large Cohort of Hematological Malignancies

To better understand the clinical relevance and biological consequences of ubiquitin-like activating enzyme (UBA1)non-M41 variants, researchers analyzed the whole genome and transcriptome data of 4168 patients with hematological malignancies.