Exosomes from CD133+ Human Urine-Derived Stem Cells Combined Adhesive Hydrogel Facilitate Rotator Cuff Healing by Mediating Bone Marrow Mesenchymal Stem Cells

In vivo experiments were performed by local injection of exosome–hydrogel complexes for the treatment of rotator cuff (RC) injury. The effects of CD133+ urine-derived stem cells-derived exosomes (USC-exos) and USC-Exos on RC healing were assessed from imaging, histological, and biomechanical tests.