NewslettersESC & iPSC NewsThe Wnt/TCF7L1 Transcriptional Repressor Axis Drives Primitive Endoderm Formation by Antagonizing Naive and Formative PluripotencyBy Noshin Noorjahan - March 8, 20230193The authors demonstrated that transcriptional repression exerted by Wnt/TCF7L1 promoted primitive endoderm differentiation of mESCs and in preimplantation inner cell mass.[Nature Communications]Full Article