Inhibition of Mammalian Target of Rapamycin Complex 1 in the Brain Microvascular Endothelium Ameliorates Diabetic Aβ Brain Deposition and Cognitive Impairment via the Sterol-Regulatory Element-Binding Protein 1/Lipoprotein Receptor-Associated Protein 1 Signaling Pathway

In vitro, brain microvascular endothelial cells were cultured with high glucose, and the activation of mTORC1 and sterol-regulatory element-binding protein 1 was observed.

[CNS Neuroscience & Therapeutics]