LncFALEC Recruits ART5/PARP1 and Promotes Castration-Resistant Prostate Cancer through Enhancing PARP1-Meditated Self PARylation

Scientists showed focally amplified long non-coding RNA on chromosome 1 (FALEC) was upregulated in post-castration tissues and castration-resistant prostate cancer cells, and increased FALEC expression was associated with poor survival in post-castration prostate cancer patients.