MUC16 Promotes Triple-Negative Breast Cancer Lung Metastasis by Modulating RNA-Binding Protein ELAVL1/HUR

The clinical significance of mucin 16 (MUC16) and ELAVL1 or Hu antigen R was examined using breast cancer TCGA data. Microarray was performed on MUC16 knockdown and scramble TNBC cells, and MUC16-associated genes were identified using RNA immunoprecipitation and metastatic cDNA array.