An IGFBP7high Endothelial Cell Subset Drives T Cell Extravasation in Psoriasis via Endothelial Glycocalyx Degradation

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Focusing on the pathogenic role of skin endothelial cells (ECs) in psoriasis, investigators characterized the molecular and functional heterogeneity of skin ECs from healthy individuals and psoriasis patients at the single-cell level.
[Journal Of Clinical Investigation]
AbstractGraphical Abstract