Repurposing Fluphenazine to Suppress Melanoma Brain, Lung and Bone Metastasis by Inducing G0/G1 Cell Cycle Arrest and Apoptosis and Disrupting Autophagic Flux

A subcutaneous tumor model, and experimental metastasis models that simulate the outgrowth of melanoma cells in the brain, lung, and bone were established to verify the inhibitory effect of FPZ on melanoma cells.