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UBL7-deficient mice exhibited increased susceptibility to viral infection due to attenuated antiviral innate immunity. UBL7 enhanced innate immune response to viral infection by promoting the K27-linked polyubiquitination of MAVS.
[Cell Reports]
UBL7 Enhances Antiviral Innate Immunity by Promoting Lys27-Linked Polyubiquitination of MAVS
