NF-κB Activator 1 Downregulation in Macrophages Activates STAT3 To Promote Adenoma-Adenocarcinoma Transition and Immunosuppression in Colorectal Cancer

Scientists ivestigated the effect of the NF-κB activator 1 downregulation of macrophages in the adenoma-adenocarcinoma transition using murine models, histological analysis, primary cell isolation, a co-culture system, and other methods.