LncRNA NEAT1 Antagonizes the Inhibition of Melanoma Proliferation, Migration, Invasion and EMT by Polyphyllin B

The authors screened NEAT1 by using LncRNA transcriptomic sequencing, and then transfected B16F10 cells using OVER-NEAT1 lentivirus. They found that Polyphyllin B had significant proliferation inhibition of melanoma and B16F10 cells through MTT assay and establishment of mouse subcutaneous transplantation tumor model.