Characterization of Mesenchymal Stem Cells in Human Fetal Bone Marrow by Single-Cell Transcriptomic and Functional Analysis

The authors reported the expression landscape of human fetal BM nucleated cells (BMNCs) based on the single-cell transcriptomic analysis. While the common cell surface markers such as CD146, CD271, and PDGFRa used for isolating MSCs were not detected, LIFR+PDGFRB+ were identified to be specific markers of MSCs as the early progenitors.