Hic1 Identifies a Specialized Mesenchymal Progenitor Population in the Embryonic Limb Responsible for Bone Superstructure Formation

Scientists showed that a subset of mesenchymal progenitors (MPs), identified by Hic1, do not contribute to the primary cartilaginous anlagen but represent the MP population, whose progeny directly contribute to the interfaces that connect bone to tendon, tendon to muscle, and the associated superstructures.