Mesenchymal Stem Cell Aggregation-Released Extracellular Vesicles Induce CD31⁺EMCN⁺ Vessels in Skin Regeneration and Improve Diabetic Wound Healing

The authors identified a specialized vasculature in skin featured by simultaneous CD31 and EMCN expression contributing to the regeneration process, the decline of which functionally underlies the impaired angiogenesis of diabetic non-healing wounds.