FN (Fibronectin)-Integrin α5 Signaling Promotes Thoracic Aortic Aneurysm in a Mouse Model of Marfan Syndrome

By
Laurisa Dohm
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Furthermore, plating of wild-type vascular smooth muscle cells (SMCs) on FN decreased contractile gene expression and activated inflammatory pathways, whereas α5/2 SMCs were resistant.
[Arteriosclerosis Thrombosis And Vascular Biology]
Abstract