Transport of Designed Ankyrin Repeat Proteins through Reconstituted Human Bronchial Epithelia and Protection against SARS-CoV-2

Transepithelial migration through air–liquid interface cultures of reconstituted human bronchial epithelia was assessed by Enzyme-Linked Immunosorbent Assays and Confocal Laser Scanning Microscopy for different DARPin designs in comparison to a monoclonal antibody.