RNF2 Inhibits E-Cadherin Transcription to Promote Hepatocellular Carcinoma Metastasis via Inducing Histone Mono-Ubiquitination

Investigators extracted data from TGCA database and validated RNF2 expression in our own cohort, which revealed that RNF2 was highly expressed in HCC and was associated with malignant characteristics and poor prognosis of HCC.