SIAH1/CTR9 Axis Promotes the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma

Researchers discovered the inhibitory effect of SIAH1 on HCC cell migration and invasion, which was related with regulating EMT. Molecularly, a yeast two-hybrid experiment indicated that CTR9 was a potential interacting protein of SIAH1, which was further verified by co-immunoprecipitation (co-IP) assays.