Upregulation of KLK8 Contributes to CUMS-Induced Hippocampal Neuronal Apoptosis by Cleaving NCAM1

Researchers explored the potential function of tissue kallikrein-related peptidase 8 (KLK8) in hippocampal neuronal cell apoptosis associated with depressive disorders in rodent models of chronic unpredictable mild stress (CUMS)-induced depression.