Endothelial Progenitor Cell-Derived Exosomes Inhibit Pulmonary Artery Smooth Muscle Cell In Vitro Proliferation and Resistance to Apoptosis by Modulating the Mitofusin-2 and Ras-Raf-ERK1/2 Signaling Pathway

Bioinformatics analysis showed that the Ras signaling pathway and exosomes (Exos) were crucial in pulmonary arterial hypertension (PAH). The PAH differential microRNAs (miRNAs) and miRNAs identified in endothelial progenitor cell-derived Exos were intersected to obtain miR-21-5p.