Heat Promotes Melanogenesis by Increasing the Paracrine Effects in Keratinocytes via the TRPV3/Ca²⁺/Hh Signaling Pathway

Researchers found that heat stress promoted melanogenesis in pigment cells by increasing the paracrine effects of keratinocytes, and high-throughput RNA sequencing showed that heat stress activated the Hedgehog (Hh) signaling pathway in keratinocytes.