NewslettersHematopoiesis NewsBCR-ABL Triggers a Glucose-Dependent Survival Program During Leukemogenesis Through the Suppression of TXNIPBy Jamie Kang - May 1, 20230133Scientists demonstrated that thioredoxin-interacting protein (TXNIP) was a novel BCR-ABL target gene. Suppression of TXNIP was responsible for BCR-ABL triggered glucose metabolic reprogramming and mitochondrial homeostasis.[Cell Death & Disease]Full Article